Hsc70 anticorps

N° du produit ABIN6653942

Cet anticorps Rat Monoclonal détecte spécifiquement Hsc70 dans WB, IHC, IP et ICC. Il présente une réactivité envers Humain, Rat, Souris, Poulet et Mammifères.

Aperçu rapide pour Hsc70 anticorps (ABIN6653942)

Antigène: Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))

Reactivité: Humain, Rat, Souris, Poulet, Mammifères

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Hsc70 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: 1B5

Détail du produit anti-Hsc70 anticorps

Specificité: Reacts with human Hsc70 (Hsp73). Cross-reacts with mouse, rat, rabbit, guinea pig, hamster, monkey, sheep, chicken, bovine, canine and porcine protein.

Purification: Purified (protein G)

Immunogène: Hsc70 purified from sodium arsenite treated heat-resistant variants of Chinese hamster cells.

Isotype: IgG2a

Information d'application

Indications d'application: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
WB0.1 μg/mL IP5 μg/mL IHC5 μg/mL ICC5 μg/mL

Positive control: HeLa Heat Shocked Cell Lysate

Restrictions: For Research Use only

Stockage

Buffer: PBS pH 7.2, 0.1 mM PMSF in 50 % glycerol.

Agent conservateur: PMSF

Stock: 4 °C/-20 °C

Stockage commentaire: Store frozen product at or below -20°C. Thawed product may be stored for 2-4 weeks at 4°C. For optimal storage, aliquot and store at -20°C.

Détails sur Hsc70

Antigène: Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))

Autre désignation: Hsc70 (Hsp73)

Sujet: Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes

Heat shock cognate 71 kDa protein Heat shock 70 kDa protein 8 Lipopolysaccharide-associated protein 1, LAP-1, LPS-associated protein 1 Gene name: HSPA8, HSC70, HSP73, HSPA10

ID gène: 3312

UniProt: P11142